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In this article, we examine study designs for extending (generalizing or transporting) causal inferences from a randomized trial to a target population. Specifically, we consider nested trial designs, where randomized individuals are nested within a sample from the target population, and nonnested trial designs, including composite data-set designs, where observations from a randomized trial are c

https://www.lupop.lu.se/article/study-designs-extending-causal-inferences-randomized-trial-target-population - 2025-12-27

A key misunderstanding is the belief that the goal of a causal analysis is to “detect” an effect. Causal effects are not binary signals that are either detected or undetected; causal effects are numerical quantities that need to be estimated. Read the paper at https://www.sciencedirect.com/science/article/abs/pii/S0895435621002730

https://www.lupop.lu.se/article/causal-analyses-existing-databases-no-power-calculations-required - 2025-12-27

I ramverket kommer vi använda kunskap om biologisk mångfald, ekologiska processer, miljöpsykologi, och epidemiologi för att hitta en gemensam väg framåt för att bemöta dessa globala utmaningar i praktiken. Vi rekryterar nu tre postdoktorer som tillsammans kommer att koordinera forskningen i projektet. Läs mer och sök tjänsterna på https://lu.varbi.com/what:job/jobID:422401/

https://www.lupop.lu.se/article/agenda-2030-postdoctoral-researcher-biodiversity-and-health - 2025-12-27

Spine surgery research has improved considerably over the last few decades. Its’ most recent growth is in large part due to the mounting increase in studies conducted using national databases and registries. With easy access to a large number of patients, the benefit of these registries has become evident. However, as with any research, this type of data must be used responsibly with the appropria

https://www.lupop.lu.se/article/big-data-registries-spine-surgery-research-lurking-dangers - 2025-12-27

Modern Epidemiology 4th is a gigantic project completed in grand style. One can only imagine all the considerations and discussions about content, terminology, ordering, et cetera that the authors had to go through and agree on to make this edition happen. Read the review at https://link.springer.com/article/10.1007%2Fs10654-021-00778-w

https://www.lupop.lu.se/article/book-review-modern-epidemiology-4th-edition - 2025-12-27

The Department of Public Health contributes to teaching in medicine, public health science, sport science and nursing. At the department, you will have approx. 200 colleagues, including 90 academic staff members and a corresponding number of PhD students. Available positions: Tenure Track Assistant Professor at the Department of Public Health Professor at the Department of Public Health

https://www.lupop.lu.se/article/available-positions-department-public-health-aarhus-university - 2025-12-27

The German RheumaDatenRhePort (RHADAR) registry encompasses a network of rheumatologists and researchers in Germany providing pseudonymized real-world patient data and allowing timely and continuous improvement in the care of RMD patients. Read the paper at https://www.jmir.org/2021/5/e28164

https://www.lupop.lu.se/article/real-world-rheumatology-registry-and-research-consortium-german-rheumadatenrheport-rhadar-registry - 2025-12-27

In this editorial, we discuss the current state-of-play of PROMs collection by kidney registries and provide an overview of what is (un)known about the feasibility and effectiveness of PROMs in CKD and other conditions. Read the paper at https://academic.oup.com/ckj/article/14/6/1495/6173985

https://www.lupop.lu.se/article/role-kidney-registries-expediting-large-scale-collection-patient-reported-outcome-measures-people - 2025-12-27

SWEDEGENE was established in 2008 and currently contains DNA and information from about 2550 adults who have experienced specific ADRs, and from 580 drug exposed controls. Read the paper at https://www.nature.com/articles/s41397-020-0148-3

https://www.lupop.lu.se/article/swedegene-swedish-nation-wide-dna-sample-collection-pharmacogenomic-studies-serious-adverse-drug - 2025-12-27

We identified 3 examples of suboptimal bias analysis, one for each common bias. For each, we describe the original research and its bias analysis, compare the bias analysis with good practices, and describe how the bias analysis and research findings might have been improved. Read the paper at https://academic.oup.com/aje/article/190/8/1604/6189735

https://www.lupop.lu.se/article/bias-analysis-gone-bad - 2025-12-27

In this paper, we describe the use of the target trial framework for designing agent-based models when the goal is estimation of causal effects in the presence of interference, or spillover. Read the paper at https://academic.oup.com/aje/article/190/8/1652/6140873

https://www.lupop.lu.se/article/emulating-target-trials-improve-causal-inference-agent-based-models - 2025-12-27

This registry is expected to provide insights into the long-term durability of different strategies of surgical repair for TAAD. Read the paper at https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019…

https://www.lupop.lu.se/article/european-registry-type-aortic-dissection-ertaad-rationale-design-and-definition-criteria - 2025-12-27

To extend previous simulations on the performance of propensity score (PS) weighting and trimming methods to settings without and with unmeasured confounding, Poisson outcomes, and various strengths of treatment prediction (PS c statistic), we simulated studies with a binary intended treatment T as a function of 4 measured covariates. Read the paper at https://academic.oup.com/aje/article/190/8/16

https://www.lupop.lu.se/article/propensity-score-weighting-and-trimming-strategies-reducing-variance-and-bias-treatment-effect - 2025-12-27

Hormonal factors and pancreatic cancer risk in women: The Malmo Diet and Cancer Study Read it here!

https://www.lupop.lu.se/article/new-publication-malmo-diet-and-cancer-study - 2025-12-27

Simulation is an important tool within epidemiology for both learning and developing new methodology. Unfortunately, few epidemiology training programs teach basic simulation methods. Read the paper at https://academic.oup.com/aje/article/190/8/1696/6140874

https://www.lupop.lu.se/article/simulation-practice-balancing-intercept - 2025-12-27

The benefits of using data from national registers as endpoints in epidemiological studies must be weighed against the impact of potentially decreased data quality. Read the paper at https://journals.sagepub.com/doi/full/10.1177/14034948211021191

https://www.lupop.lu.se/article/data-national-health-registers-endpoints-tromso-study-correctness-and-completeness-stroke-diagnoses - 2025-12-27

Unmeasured confounding is a common threat to the validity of observational studies. In practice, confounding bias may arise from both confounders that are completely unmeasured and from confounders that are measured with error. Read the paper at https://academic.oup.com/ije/article/50/3/711/6048186

https://www.lupop.lu.se/article/cautionary-note-recently-proposed-sensitivity-analysis-unmeasured-confounding - 2025-12-27

We explored the comparability of anxiety measures from register- and survey-based data including analyses of prevalence and associations with selected psychiatric and somatic diseases. Read the paper at https://onlinelibrary.wiley.com/doi/full/10.1111/acps.13339

https://www.lupop.lu.se/article/use-register-and-survey-based-measures-anxiety-population-based-danish-cohort - 2025-12-27

Immeasurable time bias exaggerates drug benefits in pharmacoepidemiological studies due to exposure misclassification arising from the inability to measure in-hospital medications in many health care databases. Read the paper at https://academic.oup.com/ije/article/50/3/987/6048410

https://www.lupop.lu.se/article/analytical-approaches-minimizing-immeasurable-time-bias-cohort-studies - 2025-12-27

Interrupted time-series (ITS) designs are a robust and increasingly popular non-randomized study design for strong causal inference in the evaluation of public health interventions. Read the paper at https://academic.oup.com/ije/article/50/3/1011/5937253

https://www.lupop.lu.se/article/reflection-modern-methods-common-error-segmented-regression-parameterization-interrupted-time-series - 2025-12-27